STD Treatment
Mfg : ChartwellDoxyPEP 100mg
Doxycycline Post-Exposure Prophylaxis (Doxy PEP) effectively prevents STI-causing bacteria when taken within 24-72 hours after sex.
Those with multiple sexual partners
Individuals engaging in condomless sex
People in open or non-monogamous relationships
Maximum Doses: 4
Per Dose $ 00.00
Total Price
Studies demonstrate DoxyPEP reduces STI acquisition when taken within 72 hours post-exposure: chlamydia incidence decreases by 70-80%, syphilis by 70-80%, and gonorrhea by 50-60%. The 2022 San Francisco study showed 65% reduction in any bacterial STI among MSM and transgender women taking DoxyPEP after condomless sex.
Current CDC guidelines suggest: single 200mg doxycycline dose within 24-72 hours after unprotected anal/vaginal sex not for routine oral sex exposure recommended primarily for gay/bisexual men and transgender women with prior STI history maximum frequency of every 24 hours always combined with standard STI screening every 3-6 months.
As a tetracycline-class antibiotic, doxycycline inhibits bacterial protein synthesis at the 30S ribosomal subunit. When administered post-exposure, it prevents establishment of chlamydia/syphilis infections and may reduce gonococcal infection severity despite increasing resistance. The prophylaxis window targets bacteria during initial mucosal invasion.
Potential side effects include GI upset (15-20%), photosensitivity (5-10%), and candidiasis (3-5%). Long-term use may contribute to antimicrobial resistance - thus reserved for high-risk scenarios. Contraindicated in pregnancy/children under 8. Not protective against HIV, HSV, HPV, or other viral STIs.
DoxyPEP should never replace condoms/PrEP but rather complement comprehensive prevention. Emerging gonorrhea resistance requires monitoring. Optimal dosing timing remains 24-72 hours post-exposure. Always follow up with full STI testing at next screening interval regardless of PEP use.
